Hydroxyapatite (HA) Powder - High Purity Calcium Hydroxylapatite for Dental & Orthopedic Applications

Princeton Powder’s high purity hydroxyapatite (HA) powder (calcium hydroxylapatite, CAS 1306-06-5) is a bioactive calcium phosphate compound engineered for superior performance in dental, orthopedic, and industrial applications. We offer fully customizable nano hydroxyapatite powder (<100 nm) and micron hydroxyapatite powder (0.1–100 μm) to match your exact formulation needs—from toothpaste remineralization to bone graft materials and industrial ceramic production. All our hydroxyapatite powder meets USP grade standards, with 99.5% trace metals purity and consistent batch-to-batch quality for global buyers in Europe and North America.

Product AttributeStandard Value
Chemical NameHydroxyapatite (Calcium Hydroxylapatite)
CAS Number1306-06-5
Purity99.5% (Trace Metals Basis) – USP Grade Hydroxyapatite Powder
Particle SizeCustomizable: Nano (<100 nm) / Micron (0.1–100 μm) / Bulk (>100 μm)
AppearanceWhite Crystalline Hydroxyapatite Powder
Grade OptionsFood Grade (for toothpaste), Biomedical Grade (orthopedic), Industrial Grade
Melting Point1100℃
Density3–3.2 g/cm³ (25°C)
Key ApplicationsDental (toothpaste remineralization), Orthopedic (bone graft)

Description of Hydroxyapatite (HA) powder

Hydroxyapatite (HA) powder, a calcium phosphate compound (Ca₁₀(PO₄)₆(OH)₂), is widely used in biomedical applications due to its biocompatibility and similarity to human bone mineral. Bulk hydroxyapatite powder is commonly used for bone grafts, dental implants, and as a coating for orthopedic implants to promote bone integration. Additionally, HA powder is utilized in chromatography for protein purification and in various research and development applications within the medical and materials science fields

Hydroxyapatite (HA) powder, available for sale in the USA, is offered in food grade, nano particle, and micro size forms. We provide a wide range of products including ceramic plates, rods, pellets, crucibles, sputtering targets, and custom shapes. Our extensive manufacturing expertise ensures reliable, tailored solutions to effectively support your projects.

Hydroxyapatite Powder Applications

1. Dental Applications (Hydroxyapatite Powder for Toothpaste & Remineralization)

Our nano hydroxyapatite powder (20–40 nm) is the gold standard for dental care products, including toothpaste, mouthwash, and desensitizer gels. It penetrates dentinal tubules to repair enamel and reduce sensitivity—making it the top choice for toothpaste manufacturers across the US and EU.
 

2. Orthopedic & Biomedical Use (Hydroxyapatite Powder for Bone Grafts)

Micron hydroxyapatite powder (15–45 μm) is ideal for bone graft materials, orthopedic implant coatings, and 3D-printed bone scaffolds. It supports osteoblast growth and osseointegration, meeting the strict standards for biomedical grade hydroxyapatite powder.
 

3. Industrial Applications

Bulk hydroxyapatite powder (>100 μm) is used in high-strength bioceramic production and environmental heavy metal adsorption, with consistent particle size and purity for industrial-scale manufacturing.

Hydroxyapatite Powder our strength

  • 99.5% high purity hydroxyapatite powder (USP grade) with batch-to-batch consistency
  • Custom particle size hydroxyapatite powder (nano/micron/bulk) tailored to your application
  • FDA/GMP/ISO certified calcium hydroxylapatite powder for global compliance
  • Fast shipping for hydroxyapatite powder to Europe and North America
  • Free samples available for nano/micron hydroxyapatite powder testing

Hydroxyapatite (HA) Powder Reference

Hydrothermal synthesis of hydroxyapatite powders using Response Surface Methodology (RSM)

  • Hydroxyapatite (HAp)—[Ca10 (PO4)6(OH) 2] has a similar chemical composition to bone material, making it the main mineral supplement in bone-making. Due to its high biocompatibility, hydroxyapatite is widely used in the repair of bone deficiencies and in the production of dental or orthopedic implants.

FAQs

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In comparison to hydroxyapatite, nano-hydroxyapatite (n-HAP) has higher solubility, surface energy and bioactivity and its structure is similar to dental apatite. Recent reports claim that Nano-HAP can be used as a remineralizing agent.

Micro-hydroxyapatite particles are at least 1,000 larger than nano-hydroxyapatite particles. They are less effective in treating dental erosion/damage because they do not interact/bind as well with the cells and surfaces in your oral microbiome. While nano-hydroxyapatite is more effective than micro hydroxyapatite.

Though it is safe for ingestion, of course we do not recommend eating it! We do recommend flossing before brushing with a toothpaste that contains hydroxyapatite so that the active ingredients can penetrate your teeth’s surface properly after the biofilm between the teeth has been removed.